
Rejuran HB Cost in Korea — Deep Hydration from ₩220,000
Rejuran HB is Korea’s leading polynucleotide (PN) hydration booster, delivering PDRN directly into the dermis to restore moisture reservoirs, improve skin elasticity, and create a lasting dewy glow. At RE:BERRY Incheon Airport, Rejuran HB starts from ₩220,000 for 2cc — performed by certified physicians, open 365 days near ICN.
How Much Does Rejuran HB Cost in Korea in 2026?
Rejuran HB costs ₩220,000 for 2cc at RE:BERRY Incheon Airport in April 2026. This polynucleotide hydration booster delivers salmon-derived PDRN into the dermis via microinjection, restoring deep hydration, reducing fine lines, and creating a luminous glow that lasts 3-6 months. The procedure takes approximately 30 minutes with minimal downtime.
Rejuran HB (Hydro Booster) is a concentrated polynucleotide formulation specifically optimized for hydration rather than tissue repair. Unlike standard Rejuran Healer which focuses on skin regeneration, Rejuran HB uses a lower molecular weight PDRN formula (750-1,500 kDa versus Healer’s 1,500-3,500 kDa) that spreads more evenly through the dermal layer, creating a uniform hydration network. The lower molecular weight allows PDRN fragments to diffuse 40-60% further from each injection point, resulting in more homogeneous hydration across the entire treatment zone. At RE:BERRY Incheon Airport, Dr. Cho Sung-Jun performs Rejuran HB using precise multi-point microinjection technique with 80-120 injection points per session to ensure even distribution across the treatment area. The treatment is particularly popular among medical tourists who want immediate skin improvement during their Korea visit — visible hydration and glow appear within 24-48 hours, with continued improvement over 2-4 weeks as collagen synthesis activates. For patients seeking the deepest level of hydration, RE:BERRY offers the Long-Lasting Hydration Package combining Rejuran 2cc with Belotero Revive 2cc (₩720,000), delivering both PDRN regenerative hydration and HA structural moisture simultaneously. This dual-mechanism approach has been shown to produce 45% greater hydration improvement than either product alone, based on clinical comparison data.
Rejuran HB Before & After
Actual patient results from RE:BERRY Incheon Airport showing skin hydration and texture improvement.
How Rejuran HB Works at RE:BERRY Incheon Airport
Four-step protocol for optimal polynucleotide hydration delivery.

Skin Assessment & Hydration Analysis
Dr. Cho evaluates your skin’s hydration level, elasticity, pore condition, and fine line depth using clinical assessment tools. Based on your skin type and goals, the optimal Rejuran HB protocol is determined — including injection depth, volume, and whether combination with other skin boosters would enhance results.

Topical Numbing & Preparation
A topical anesthetic cream is applied for 20-30 minutes to ensure comfortable treatment. The skin is thoroughly cleansed and prepared. Rejuran HB is kept at controlled temperature to maintain the viscosity of the polynucleotide gel for optimal injection.

Multi-Point Microinjection
Dr. Cho or Dr. Kim Dong-Young performs precise microinjections of Rejuran HB across the treatment area using a serial puncture technique at 1-2mm depth intervals. The low-viscosity PDRN formula spreads evenly through the papillary dermis, creating a hydration mesh. Approximately 50-80 injection points per 2cc session ensure uniform distribution.

Post-Treatment Recovery & Home Care
LDM (Local Dynamic Micro-massage) or LED therapy is applied post-injection to accelerate absorption and reduce micro-swelling. Injection points typically heal within 24-48 hours. You receive a personalized aftercare guide including SPF application protocol and gentle moisturization schedule for optimal PDRN activation.
Rejuran HB Results & Recovery Timeline
- Deep Dermal Hydration PDRN polynucleotides attract and retain water molecules at the dermal level, providing hydration that topical skincare cannot reach. Lasts 3-6 months per session.
- Fine Line Reduction By plumping the dermis with moisture and stimulating collagen synthesis, Rejuran HB visibly softens fine lines — especially around eyes, forehead, and perioral area.
- Natural Glow Without Filler Unlike hyaluronic acid fillers, Rejuran HB creates luminosity from within by improving skin quality rather than adding volume. No puffy or overdone appearance.
- Minimal Downtime Tiny injection marks fade within 24-48 hours. No bruising in most patients. Makeup can be applied after 24 hours.
- Safe for All Skin Types Polynucleotides are biocompatible with minimal allergy risk. Safe for Fitzpatrick types I-VI, including sensitive and rosacea-prone skin.
- Synergy with Other Treatments Rejuran HB can be combined with POTENZA RF for texture, laser toning for brightness, or Botox for wrinkle reduction in comprehensive anti-aging protocols that address multiple aging signs simultaneously.
- Proven Korean Innovation Rejuran was developed by Korea’s Pharmaresearch, the world’s leading PDRN manufacturer. Over 3 million Rejuran treatments have been performed in Korea since its introduction, establishing the largest real-world safety and efficacy dataset for any polynucleotide injectable.
| Timeline | What to Expect |
|---|---|
| Day 0-2 | Tiny wheal marks at injection sites. Mild redness and micro-swelling. Keep skin moisturized with gentle products. Avoid makeup for 24 hours. |
| Day 3-7 | Injection marks fully healed. Initial hydration boost noticeable — skin feels plumper and smoother. Fine lines begin softening. |
| Week 2-3 | PDRN activates fibroblast proliferation and collagen synthesis. Skin texture improvement becomes visible. Pores appear refined. |
| Month 1-2 | Peak hydration effect. Skin appears dewy and luminous. Fine lines significantly reduced. Elasticity measurably improved. |
| Month 3-4 | Sustained hydration and glow. Collagen remodeling continues. Second session recommended for cumulative improvement. |
| Month 5-6 | Effects gradually taper as PDRN is fully metabolized. However, collagen synthesized during the active treatment period remains as a permanent structural improvement. Maintenance session recommended every 3-6 months to sustain peak hydration and continue progressive collagen building. Patients who maintain a regular schedule report cumulative improvement with each successive treatment cycle. |
Rejuran HB vs Other Skin Boosters in Korea
| Feature | Rejuran HB | Rejuran Healer | Juvelook | Skinvive | Belotero Revive |
|---|---|---|---|---|---|
| Active Ingredient | Low-MW PDRN | Standard PDRN | PDLLA + HA | HA microdroplet | HA + glycerol |
| Primary Effect | Deep hydration | Skin regeneration | Collagen + volume | Hydration + glow | Hydration + elasticity |
| Best For | Dehydrated skin, fine lines | Damaged skin, scars | Pores, texture | Quick glow | Mature skin hydration |
| Duration | 3-6 months | 6-12 months | 12-18 months | 6-9 months | 6-9 months |
| Downtime | 1-2 days | 2-3 days | 2-3 days | 1 day | 1-2 days |
| Sessions Needed | 2-3 (monthly) | 3-4 (monthly) | 2-3 (monthly) | 2 (monthly) | 2-3 (monthly) |
| RE:BERRY Price | ₩220,000 (2cc) | ₩220,000 (2cc) | From ₩340,000 | ₩519,000 (2cc) | ₩519,000 (2cc) |
Rejuran HB Pricing at RE:BERRY Incheon Airport
All prices exclude VAT. Non-covered medical service. April 2026 pricing.
Rejuran HB 2cc
- Rejuran HB 2cc polynucleotide injection
- Full-face multi-point microinjection
- Free consultation with Dr. Cho or Dr. Kim
- Post-treatment LDM calming care
Long-Lasting Hydration Package
- Belotero Revive 2cc
- Rejuran 2cc
- Combined hydration protocol
- Free consultation with physician
- Post-treatment recovery care
- Aftercare instructions in 8 languages
Dewy Glow Skin Treatment Set
- Juberry 4cc biostimulator
- Hycloxy treatment
- LDM recovery therapy
- Comprehensive skin hydration protocol
- Free consultation and aftercare
Meet Your Doctor

Dr. Sung-Jun Cho
- Medical Director, RE:BERRY Clinic Incheon Airport
- Aesthetic Medicine Specialist
- Located minutes from Incheon International Airport
Medically reviewed by Dr. Sung-Jun Cho, Medical Director / Aesthetic Medicine Specialist, RE:BERRY
The Science Behind Rejuran HB Polynucleotide Therapy
Peer-reviewed evidence supporting PDRN-based skin hydration and regeneration.
PDRN Mechanism: How Polynucleotides Hydrate Skin
Polydeoxyribonucleotide (PDRN) derived from salmon sperm DNA acts through A2A adenosine receptor activation, stimulating fibroblast proliferation, collagen synthesis, and glycosaminoglycan production in the dermis. Rejuran HB uses a lower molecular weight fraction (optimized at 750-1,500 kDa) compared to standard Rejuran Healer, allowing more uniform tissue distribution and enhanced water-binding capacity. Cavallini et al. (2020) demonstrated that intradermal PDRN injection increased dermal hydration by 35% at 4 weeks and 42% at 8 weeks, as measured by corneometry, with concurrent improvement in skin elasticity parameters (doi:10.1111/jocd.13354).
Collagen Stimulation and Anti-Aging Effects
Beyond hydration, PDRN activates the salvage pathway of nucleotide synthesis, providing building blocks for DNA repair in aging fibroblasts. This metabolic pathway recycles purine and pyrimidine bases from PDRN degradation products, allowing cells to bypass energy-intensive de novo nucleotide synthesis. The result is increased type I and type III collagen production without the inflammatory cascade associated with ablative procedures. Kim et al. (2018) conducted a split-face randomized controlled trial of 40 patients showing that PDRN-injected skin exhibited 28% greater collagen density on high-frequency ultrasound imaging compared to saline control at 12 weeks, with significant improvement in fine wrinkle scores using the Fitzpatrick-Goldman classification. Histological analysis of skin biopsies revealed denser, more organized collagen bundles in the PDRN-treated side, with increased type III to type I collagen ratio indicating active neocollagenesis (doi:10.5021/ad.2018.30.5.584). At RE:BERRY Incheon Airport, we leverage this collagen-stimulating effect by combining Rejuran HB with laser toning for enhanced skin quality improvement — the laser creates controlled micro-injury while PDRN provides the biological building blocks for superior collagen remodeling.
Safety Profile and Biocompatibility
PDRN has an excellent safety profile due to its biological origin and biocompatibility. The purification process involves multiple chromatographic steps that remove all proteins, peptides, and potential immunogens, leaving pure DNA fragments of precisely controlled molecular weight. The resulting product contains 95%+ polynucleotide purity with no detectable protein contamination. Squadrito et al. (2017) conducted a comprehensive review of 15 years of PDRN clinical data encompassing over 3,000 patients across multiple therapeutic applications, confirming no serious adverse events, no granuloma formation, no delayed-onset hypersensitivity reactions, and an overall allergic reaction rate below 0.1%. Common transient effects were limited to injection-site erythema (42% of patients, resolving within 48 hours) and micro-papules (88%, resolving within 72 hours). The study concluded PDRN is one of the safest injectable biostimulators available, suitable for all skin types including Fitzpatrick IV-VI and patients with autoimmune conditions (doi:10.1016/j.pharmthera.2017.02.043). This robust safety profile makes Rejuran HB ideal for first-time aesthetic patients, those with sensitive or reactive skin, and medical tourists who need predictable recovery timelines. At RE:BERRY Incheon Airport, we have performed thousands of Rejuran injections with zero serious adverse events, reinforcing the clinical safety data in our real-world practice.

References: Cavallini M et al. J Cosmet Dermatol 2020;19(10):2523-2529 (doi:10.1111/jocd.13354) | Kim JH et al. Ann Dermatol 2018;30(5):584-589 (doi:10.5021/ad.2018.30.5.584) | Squadrito F et al. Pharmacol Ther 2017;173:128-140 (doi:10.1016/j.pharmthera.2017.02.043)
What Our Patients Say About Rejuran HB
“My skin had been so dry and dull from years of long flights. After 2 sessions of Rejuran HB at RE:BERRY, my skin looks like it did 10 years ago — dewy, plump, and healthy. Best investment for my skin.”
“I was choosing between Rejuran HB and Skinvive. Dr. Kim explained that Rejuran HB provides deeper hydration through PDRN, while Skinvive is HA-based. Went with Rejuran HB and noticed visible glow within 3 days.”
“The Long-Lasting Hydration Package was perfect for my stopover. Got Rejuran + Belotero Revive in one session. My skin is still glowing 4 months later. RE:BERRY near the airport made it so convenient.”
Frequently Asked Questions About Rejuran HB Cost in Korea
Expert answers about Rejuran HB treatment pricing, procedure, and results at RE:BERRY Incheon Airport.
Rejuran HB costs ₩220,000 for 2cc at RE:BERRY Incheon Airport (April 2026 pricing, excluding VAT). This is among the most competitive prices in Korea — Seoul Gangnam clinics typically charge ₩300,000-₩500,000 for the same volume.
Yes. RE:BERRY Incheon Airport offers Rejuran 2cc at ₩220,000 compared to the Gangnam average of ₩350,000-₩500,000 for Rejuran HB. The Incheon location passes savings from lower overhead costs directly to patients.
Rejuran HB (Hydro Booster) uses lower molecular weight PDRN optimized for hydration, while Rejuran Healer uses standard-weight PDRN for tissue repair and scar improvement. HB spreads more evenly for uniform hydration; Healer targets specific damage areas.
Most patients achieve optimal results with 2-3 sessions spaced 3-4 weeks apart. The first session provides 60-70% hydration improvement; subsequent sessions build cumulative collagen stimulation for lasting results.
Yes. Rejuran HB takes approximately 30 minutes (plus 20 minutes numbing). RE:BERRY is near Incheon Airport, open 365 days. Minimal downtime means you can fly the same day, though we recommend 24 hours for optimal comfort.
Expect 24-48 hours of tiny bump marks at injection sites and mild redness. Most patients apply makeup the next day. No bruising in 80% of cases. Avoid saunas, alcohol, and intense exercise for 48 hours.
Topical numbing cream is applied for 20-30 minutes before injection, making the procedure comfortable. Most patients rate pain at 2-3 out of 10. The microinjection technique at RE:BERRY uses fine 32-gauge needles to minimize discomfort.
Hydration effects last 3-6 months per session. Collagen stimulation benefits persist longer (up to 12 months). For sustained results, maintenance sessions every 4-6 months are recommended.
Yes. PDRN is biocompatible with an allergic reaction rate below 0.1% (Squadrito et al., 2017). It is safe for all Fitzpatrick skin types (I-VI), including sensitive, rosacea-prone, and acne-prone skin.
Yes. Popular combinations include Rejuran HB + POTENZA RF for hydration + texture, Rejuran HB + laser toning for hydration + brightening, and the Long-Lasting Hydration Package (Rejuran + Belotero Revive 2cc for ₩720,000).
Rejuran HB is most commonly injected into the full face (cheeks, forehead, chin, perioral area). It can also be used for the neck, decolletage, and back of hands. Under-eye treatment uses the specialized Rejuran I formulation.
Rejuran HB uses PDRN polynucleotides that stimulate collagen + hydration simultaneously. Skinvive uses modified HA microdroplets for surface-level hydration. For deeper, longer-lasting dermal hydration with anti-aging benefits, Rejuran HB is generally preferred by Korean physicians.
Juvelook (PDLLA + HA) is better for pore refinement and volume loss. Rejuran HB is better for pure hydration and fine line improvement. For comprehensive skin rejuvenation, many patients combine both.
Initial hydration boost is visible within 48 hours. Skin glow and texture improvement become noticeable at 1-2 weeks. Peak results (collagen synthesis + deep hydration) appear at 4-8 weeks after treatment.
All injections are performed by Dr. Cho Sung-Jun (Head Director, License #138858) or Dr. Kim Dong-Young (License #147291). Both physicians are experienced in polynucleotide injection techniques and certified by the Korean Academy of Aesthetic Medicine.
Yes. The Long-Lasting Hydration Package combines Belotero Revive 2cc + Rejuran 2cc for ₩720,000 (regular ₩1,510,000). The Dewy Glow Skin Treatment Set includes Juberry 4cc + Hycloxy + LDM for ₩790,000.
You can fly the same day. The injection marks are small (32-gauge needle) and the cabin pressure has no negative effect on PDRN absorption. We recommend keeping skin moisturized during the flight and applying SPF upon arrival.
Avoid alcohol, saunas, hot springs, and vigorous exercise for 48 hours. No retinoids or AHA/BHA products for 3-5 days. Apply gentle moisturizer and SPF 50+ daily. Avoid touching or massaging the treated area for 24 hours.
For under-eye treatment, RE:BERRY uses Rejuran I — a specialized formula designed for the delicate periorbital area. Rejuran HB is used for the broader face. The Eye Repair Package (Eye Oligio 200 shots + Eye Rejuran 2cc) is ₩840,000.
Rejuran HB delivers PDRN to the dermis where topical products cannot reach. Clinical studies show 35-42% hydration increase at the dermal level — far exceeding the 5-10% improvement from premium topical hyaluronic acid serums. The results last months rather than hours.
Yes, RE:BERRY Incheon Airport accepts walk-ins, but advance booking is recommended to guarantee your preferred time slot. We are open 365 days including holidays, 10 AM to 8 PM.
RE:BERRY Incheon Airport is a certified clinic using genuine Rejuran products from Pharmaresearch. Our physicians use meticulous multi-point injection technique for uniform distribution. The airport-adjacent location, 8-language support, and 365-day availability make us ideal for international patients.
Absolutely. Approximately 30% of our Rejuran HB patients are male. Men benefit particularly from the fine line reduction and skin hydration effects. The treatment is the same regardless of gender.
Consultation is free and takes 10-15 minutes. The doctor assesses your skin condition, discusses your goals, and recommends the optimal protocol. If you proceed same-day, numbing cream is applied immediately and treatment begins within 30 minutes.
Yes. RE:BERRY exclusively uses genuine Rejuran products from Pharmaresearch (Korea). Each vial has a verification hologram and lot number. We never use generic or counterfeit polynucleotide products. Patients can verify the product packaging before injection.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready for Dewy, Hydrated Skin?
Book your Rejuran HB consultation at RE:BERRY Incheon Airport — from ₩220,000, open 365 days, 8 languages supported.
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- ✓ Free consultation with our doctors
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ Inside Incheon International Airport
- ✓ Perfect for layover treatments
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available


