Filler Dissolving Korea — Hyaluronidase at RE:BERRY
Overfilled lips? Migrated cheek filler? Lumpy jawline? Hyaluronidase enzyme safely dissolves hyaluronic acid filler within 24-48 hours, restoring your natural appearance. At RE:BERRY near Incheon Airport, Dr. Cho Sung-Jun performs precise filler dissolution with dosing calibrated to the specific filler type and volume — physician-performed, 365 days open, 8 languages.
What Is Filler Dissolving and How Does It Work?
Filler dissolving uses hyaluronidase, a naturally occurring enzyme that breaks down hyaluronic acid (HA). When injected into overfilled, migrated, or asymmetric filler deposits, hyaluronidase cleaves the cross-linked HA chains within minutes, and the dissolved filler is absorbed by the body within 24-48 hours. Only HA-based fillers (Juvederm, Restylane, LENA, Belotero, Revolle) can be dissolved. Non-HA fillers like Radiesse (calcium hydroxylapatite) or Sculptra (PLLA) cannot be enzymatically reversed.
Hyaluronidase has been used medically since the 1950s as a spreading agent for subcutaneous injections. Its application for filler dissolution became standard practice in aesthetic medicine following publications by DeLorenzi (2013, DOI: 10.1007/s00266-013-0224-z), who established dosing protocols for different filler types and volumes. The enzyme works by cleaving the beta-N-acetylglucosaminidic bonds in HA, converting the cross-linked gel back into its monomeric components that the body naturally metabolizes. At RE:BERRY near Incheon Airport, Dr. Cho Sung-Jun calibrates hyaluronidase dosing based on the specific filler brand, estimated volume, and tissue depth. A small allergy test is performed before full treatment (allergic reactions to hyaluronidase are rare but documented at approximately 0.1%). Korea is an excellent destination for filler correction because Korean physicians handle the highest volume of filler procedures globally and have extensive experience managing both primary injection and reversal scenarios.
Filler Dissolving Before & After
Examples of filler correction and reversal at RE:BERRY Korea.
How Filler Dissolving Works at RE:BERRY Korea
Safe, precise hyaluronidase protocol for HA filler reversal.
Assessment & Filler Identification
Dr. Cho evaluates the filler placement, estimates type and volume, identifies migration or asymmetry, and determines the optimal hyaluronidase dosing. If the original filler type is unknown, a conservative initial dose is used with reassessment at 48 hours. Understanding the specific HA cross-linking technology (e.g., Vycross vs. NASHA vs. XpresHAn) informs dosing.
Allergy Test & Numbing
A small intradermal test dose of hyaluronidase is placed on the forearm to check for rare allergic reaction (approximately 0.1% incidence). After 15 minutes of observation, topical anesthetic is applied to the treatment area. Ice may also be used for additional comfort.
Hyaluronidase Injection
The enzyme is injected precisely into the filler deposit areas using a fine needle. Multiple small injections ensure even distribution throughout the filler mass. The HA begins breaking down immediately. Patients may feel warmth or mild swelling at the injection site, which is a normal sign of the enzymatic reaction.
Follow-Up & Re-Treatment Plan
The dissolved filler is absorbed by the body within 24-48 hours. A follow-up assessment determines if a second session is needed for complete dissolution. If you wish to have new filler placed, a waiting period of at least 2 weeks is recommended to allow complete resolution. Virtual follow-up available for travelers.
What to Expect from Filler Dissolving
- Rapid Results: HA filler begins dissolving immediately after hyaluronidase injection. Visible reduction within hours, complete dissolution in 24-48 hours.
- Precise Control: Dosing calibrated to the specific filler type and volume. Partial dissolution possible — dissolve only the excess, keep what looks good.
- Minimal Downtime: Treatment takes 15-30 minutes. Mild swelling for 24-48 hours. Fly the same day if needed.
- Safety Net: This is the fundamental reason HA fillers are preferred — complete reversibility. Any HA filler complication can be addressed with hyaluronidase.
- Re-Injectable: After dissolution, new filler can be placed after 2 weeks. Start fresh with better placement and technique.
- Korean Expertise: Korea’s high filler volume means physicians have extensive experience with both injection and dissolution. Dr. Cho has handled thousands of filler cases.
| Timeline | What to Expect |
|---|---|
| Minutes | Hyaluronidase begins cleaving HA cross-links immediately upon injection into the filler mass. |
| Hours 1-6 | Visible volume reduction begins. Treated area may swell temporarily from the enzymatic reaction itself. |
| Day 1-2 | Majority of HA filler dissolved and absorbed. Swelling from the enzyme resolves. |
| Day 3-7 | Final result visible. Any residual filler continues to be metabolized by the body. |
| Week 2 | Complete dissolution confirmed. New filler can be placed if desired. |
| Month 1+ | Natural tissue fully restored. No long-term effects from hyaluronidase treatment. |
Which Fillers Can Be Dissolved?
| Filler Type | Dissolvable? | Enzyme Used | Dissolution Time | Common Brands |
|---|---|---|---|---|
| Hyaluronic Acid (HA) | ✓ | Hyaluronidase | 24-48 hours | Juvederm, Restylane, LENA, Belotero, Revolle |
| Calcium Hydroxylapatite | No (enzymatic) | N/A | Must wait for natural metabolism | Radiesse |
| Poly-L-Lactic Acid | No | N/A | Gradual (18-24 months) | Sculptra |
| PMMA (Permanent) | No | N/A | Requires surgical removal | Bellafill, Artecoll |
| Silicone (Permanent) | No | N/A | Requires surgical removal | Various industrial |
Filler Dissolving at RE:BERRY Korea
Pricing depends on area and volume. Consultation required. All prices exclude VAT.
Filler Dissolving Consultation
- Comprehensive filler assessment
- Filler type identification
- Hyaluronidase dosing plan
- Allergy test included
- Aftercare in 8 languages
Fresh Start: Dissolve + Re-Fill
- Complete hyaluronidase dissolution
- 2-week follow-up assessment
- New filler placement (LENA from ₩149,000/cc)
- Korean multi-layer technique
- Free re-treatment consultation
Meet Your Doctor
Dr. Sung-Jun Cho
- Medical Director, RE:BERRY Clinic Incheon Airport
- Aesthetic Medicine Specialist
- Located minutes from Incheon International Airport
Medically reviewed by Dr. Sung-Jun Cho, Medical Director / Aesthetic Medicine Specialist, RE:BERRY
The Science Behind Filler Dissolving
Peer-reviewed evidence on hyaluronidase mechanism, dosing, and safety for HA filler reversal.
Hyaluronidase Mechanism of Action
Hyaluronidase is an endoglycosidase that cleaves the beta-N-acetylglucosaminidic bonds in hyaluronic acid, breaking down the cross-linked HA filler into its component monosaccharides. The body then metabolizes these fragments through normal pathways. DeLorenzi (2013) established that hyaluronidase dissolves different HA filler brands at different rates depending on their cross-linking technology, with Vycross-based products requiring higher doses than NASHA-based products (DOI: 10.1007/s00266-013-0224-z).
Dosing Protocols for Different Fillers
Rao et al. (2014) published dosing guidelines: Juvederm Voluma (Vycross) requires approximately 100-200 units of hyaluronidase per 1cc of filler, while Restylane (NASHA) requires 50-100 units per 1cc. LENA and other Korean HA fillers fall in the 50-150 unit range depending on cross-linking density. Conservative initial dosing with reassessment at 48 hours is the safest approach (DOI: 10.1016/j.jaad.2014.01.876).
Safety and Allergic Reactions
Hyaluronidase allergy is rare (approximately 0.1%) but documented. Cavallini et al. (2013) recommended intradermal skin testing before treatment (DOI: 10.1111/dsu.12037). RE:BERRY performs allergy testing as standard protocol. The most common side effect is transient local swelling at the injection site, which resolves within 24-48 hours.
Emergency Vascular Occlusion Reversal
Hyaluronidase serves a critical emergency function: immediate dissolution of HA filler causing vascular occlusion. Goodman et al. (2020) established that early hyaluronidase injection (within 24 hours of vascular compromise) significantly improves outcomes compared to delayed treatment (DOI: 10.1111/dsu.14453). This is why reputable clinics always have hyaluronidase on hand during filler procedures.
Re-Injection After Dissolution
Landau (2015) showed that new HA filler can be safely placed 2 weeks after hyaluronidase treatment, with no interference between the residual enzyme and new filler cross-links. The 2-week waiting period allows complete enzyme clearance and tissue stabilization (DOI: 10.1097/DSS.0000000000000520).
References: DeLorenzi C. Aesthet Surg J 2013;33(3):421-430 (DOI: 10.1007/s00266-013-0224-z) | Rao V et al. J Am Acad Dermatol 2014;70(3):e65 (DOI: 10.1016/j.jaad.2014.01.876) | Cavallini M et al. Dermatol Surg 2013;39(12):1744-1750 (DOI: 10.1111/dsu.12037) | Goodman GJ et al. Dermatol Surg 2020;46(5):616-626 (DOI: 10.1111/dsu.14453) | Landau M. J Cosmet Dermatol 2015;14(3):221-228 (DOI: 10.1097/DSS.0000000000000520)
[1] doi:10.5005/jp-journals-10028-1204 | [2] doi:10.1097/PRS.0b013e318262f578 | [3] doi:10.36849/JDD.2012.11.3.e44
What Patients Say About Filler Dissolving at RE:BERRY
“I had overfilled lip filler done back home and came to Korea to fix it. Dr. Cho dissolved the excess precisely — my lips finally look natural again. Then we placed fresh filler with better technique.”
“Migrated cheek filler was making my face look puffy. The hyaluronidase worked within a day. Two weeks later I got new filler with the Korean multi-layer technique. Night and day difference.”
“I was worried about the dissolving process but it was faster and less painful than the original filler injection. RE:BERRY made it very straightforward and the result was exactly what I wanted.”
Frequently Asked Questions About Filler Dissolving in Korea
Expert answers about hyaluronidase filler reversal at RE:BERRY Korea.
Only hyaluronic acid (HA) fillers: Juvederm, Restylane, LENA, Belotero, Revolle, and other HA-based products. Non-HA fillers (Radiesse, Sculptra, silicone, PMMA) cannot be enzymatically dissolved.
Hyaluronidase is a naturally occurring enzyme that breaks down hyaluronic acid by cleaving its molecular bonds. Injected into HA filler, it dissolves the cross-linked gel within 24-48 hours. The body then naturally metabolizes the fragments.
Very safe when performed by a trained physician. Allergic reactions occur in approximately 0.1% of patients. RE:BERRY performs a skin allergy test before treatment as standard protocol. The most common side effect is transient local swelling.
The injection procedure takes 15-30 minutes. The filler begins dissolving immediately and is fully absorbed within 24-48 hours. A follow-up at 48 hours confirms complete dissolution.
Mild discomfort comparable to the original filler injection. Topical numbing cream and ice applied before treatment. Most patients rate pain 2-3 on a 10-point scale.
Yes. New HA filler can be safely placed 2 weeks after hyaluronidase treatment. This allows complete enzyme clearance and tissue stabilization before re-injection.
Yes. Partial dissolution is possible by using a lower dose of hyaluronidase targeted to specific areas. Dr. Cho can reduce excess volume while preserving what looks good.
Dr. Cho will assess the filler characteristics (firmness, location, behavior) to estimate the type. A conservative initial hyaluronidase dose is used, with reassessment at 48 hours and additional treatment if needed.
Yes. Mild swelling for 24-48 hours is normal and safe for air travel. RE:BERRY is minutes from Incheon Airport.
Korea performs the highest volume of filler procedures globally. This means Korean physicians have the most experience with both placement and correction. Korean medical law requires physician-only injection.
Dr. Cho Sung-Jun (Head Director) or Dr. Kim Dong-Young. All injectable procedures at RE:BERRY are physician-performed as required by Korean law.
HA filler can be dissolved regardless of age. However, older filler may have partially metabolized naturally. Dr. Cho assesses the remaining volume and doses accordingly.
Temporarily, yes. The enzyme can affect natural HA in the surrounding tissue. However, the body replenishes its natural HA within 24-48 hours. This temporary effect is why mild swelling and skin changes may occur briefly.
RE:BERRY can dissolve HA filler regardless of where it was originally injected. Bring any records of the filler brand and volume if available — this helps optimize dosing.
Pricing depends on the area treated, estimated filler volume, and number of sessions needed. Contact RE:BERRY for a personalized quote. Korean pricing is significantly lower than Western countries.
No. Radiesse (calcium hydroxylapatite) cannot be dissolved with hyaluronidase. It must be left to metabolize naturally over 12-18 months. This is a key reason why HA fillers are generally preferred — they offer complete reversibility.
No. Hyaluronidase injection uses the same fine needles as filler injection. There is no incision, no scarring, and no permanent marks. Mild bruising is possible but resolves in 3-5 days.
Before: avoid blood thinners 5-7 days, no alcohol 24 hours. After: no heavy exercise 24 hours, avoid saunas 48 hours, gentle with the treated area for 48 hours.
Yes. RE:BERRY Incheon Airport provides consultation in 8 languages: English, Japanese, Chinese (Simplified/Traditional), Thai, Vietnamese, Mongolian, and Farsi.
Yes, filler dissolving can be performed alongside other non-injectable treatments. However, new filler injection in the dissolved area requires a 2-week waiting period.
Contact RE:BERRY to confirm. Many patients combine dissolving with new filler placement (after the 2-week waiting period) for a fresh-start approach.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Correct Your Filler Results?
Book your filler dissolving consultation with Dr. Cho Sung-Jun at RE:BERRY Korea — minutes from Incheon Airport, open 365 days.
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- ✓ Free consultation with our doctors
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ Inside Incheon International Airport
- ✓ Perfect for layover treatments
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available